
Polynucleotides
Subtle tweaks. Safe hands. Beautiful results.
At Bloom by J in Farnham, we offer advanced polynucleotide treatments designed to improve skin quality from within. Unlike dermal fillers, which restore volume and structure, polynucleotides work by supporting the skin’s natural regenerative processes to improve hydration, elasticity, firmness and texture.
Polynucleotides are naturally derived DNA fragments that act as biostimulators within the skin, supporting its natural repair and regeneration. The result is a gradual improvement in skin quality, helping skin appear smoother, firmer, healthier and more resilient.
Polynucleotides can help to:
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Support natural skin regeneration and repair
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Improve hydration and skin quality
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Support collagen and elastin production
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Improve firmness, elasticity and texture
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Soften the appearance of fine lines and crepey skin
Rather than adding volume or changing your facial shape, polynucleotides are designed to improve the quality and condition of your skin for a naturally refreshed result.
Polynucleotides are long chains of naturally occurring DNA fragments that act as biostimulators when injected into the deeper layers of the skin. They support and enhance the skin’s natural repair processes by activating fibroblasts — the cells responsible for producing collagen and elastin — leading to improved elasticity, hydration, texture, and overall skin resilience.
Rather than adding bulk or shape, polynucleotides:
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Boost skin regeneration and cellular repair
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Improve hydration by attracting and retaining moisture deep in the dermis
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Stimulate natural collagen and elastin production for better texture and firmness
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Reduce oxidative stress and inflammation within the skin
This makes the treatment ideal for patients wanting a healthier, more radiant complexion without the look of structural augmentation.
Areas we Treat
At Bloom By J, we use polynucleotide injections to improve skin quality in multiple areas, including:
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Face (overall rejuvenation)
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Under-eye area (delicate skin support)
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Neck & décolletage (firmness & tone)
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Body (signs of ageing, scars & stretch marks)
Before any treatment begins, we recommend booking a free, no-obligation consultation. This allows us to get to know you, understand your individual concerns, and create a personalised treatment plan — whether for a single concern or ongoing aesthetic care.
During your consultation, we’ll take the time to explain each suggested treatment in detail, ensuring you have all the information you need to make an informed and confident decision about moving forward. Our focus is always on safety, transparency, and helping you feel completely at ease.

Face
Polynucleotide treatment for the face focuses on improving overall skin quality rather than altering facial structure. By stimulating collagen production and enhancing cellular repair, it helps refine texture, improve elasticity, and restore hydration. The result is smoother, firmer, more radiant skin with a natural, refreshed appearance.

Neck and décolletage
The neck and chest are often early indicators of ageing due to thinner skin and sun exposure. Polynucleotides work to improve firmness, elasticity, and skin tone in these areas, helping to smooth fine lines and restore a more even, youthful appearance.

Under-Eye
The under-eye area is one of the thinnest and most fragile areas of the face. Polynucleotides help strengthen and regenerate this delicate skin, improving crepey texture, fine lines, and signs of tiredness. This treatment supports skin health without adding volume, making it ideal for those wanting subtle rejuvenation.

Body
The skin on the body can show signs of ageing through thinning, dryness, loss of elasticity and changes in texture. Polynucleotide treatments can support skin regeneration and improve hydration, firmness and resilience in areas such as the neck, décolletage, arms, abdomen, thighs, stretch marks and scars.
Polynucleotide Benefits
Polynucleotide treatments are ideal for improving overall skin health and targeting early to moderate signs of ageing. Rather than masking concerns, they work at a cellular level to regenerate and strengthen the skin from within.
Polynucleotides are commonly used to help improve:

Softens the appearance of early expression lines and age-related creasing by supporting natural collagen renewal.

Improves mild to moderate skin looseness that can develop with age or weight changes.

Enhances deep hydration in skin compromised by seasonal weather changes, and restores radiance to skin affected by stress, poor sleep, or lifestyle factors.

Strengthens fragile, paper-like skin often associated with ageing, particularly around the eyes, neck, and hands.

Supports delicate under-eye skin that has thinned with age or shows signs of fatigue

Helps repair skin affected by UV exposure, pollution, and other environmental aggressors.

Encourages regeneration in areas with post-acne marks or uneven surface texture.

Calms and strengthens skin that may be prone to conditions such as mild rosacea or sensitivity.
Our Polynucleotide Treatments
Plenhyage®
Plenhyage® supports the skin’s natural regenerative processes to improve hydration, elasticity, firmness and texture. Available in different formulations to suit different areas, skin concerns and treatment goals, it can be used across the face and body to address visible signs of ageing and compromised skin quality, creating healthier, smoother and more resilient-looking skin.

Ameela® Eyes
Ameela® Eyes is specifically formulated for the delicate skin around the eyes, helping improve hydration, elasticity and skin quality. It can help soften the appearance of fine lines, crepey skin and tired-looking eyes, while supporting the appearance of dark circles and mild under-eye hollowness where these are related to skin quality. It does not replace lost volume in the way a dermal filler can.

Which Polynucleotide is Right For Me?
Plenhyage® S
Fine, delicate skin rejuvenation
Best For:
Fine lines, hydration, texture and delicate areas
Plenhyage® m
General skin regeneration
Best For:
Face, neck, décolletage; firmness, elasticity, texture
Plenhyage® xl
More intensive regeneration & skin remodelling
Best For:
More pronounced laxity, deeper lines and areas requiring greater structural skin support
Ameela® Eyes
Specialist eye rejuvenation
Best for:
Under-eye fine lines, crepey texture, dehydration and elasticity
At a Glance
Treatment Time
45-60 Minutes
Results visible
Over a Few Weeks
Anaesthetic
Used as Required
Longevity
6-12 Months
Downtime
Minimal
Review
3-4 Weeks
Treatment Menu
Title | Price From |
|---|---|
Plenhyage | 1 Treatment | 180 |
Plenhyage | 2 Treatments | 340 |
Plenhyage | 3 Treatments | 500 |
Ameela Eyes | 1 treatment | 190 |
Ameela Eyes | 2 Treatments | 360 |
Ameela Eyes | 3 Treatments | 530 |
30 min
1 hr
From 180 British pounds
Disclaimer
At Bloom By J, we aim to provide safe, effective, polynucleotide treatments. However, it’s important to understand that every individual is unique, and results may vary.
Factors that can influence your outcome include:
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Skin type, condition and sensitivity
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Age, skin elasticity and natural regenerative capacity
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The extent of dehydration, fine lines or loss of firmness
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Lifestyle factors, including sun exposure, smoking, diet and hydration
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Previous aesthetic treatments or skincare
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Your individual response to treatment and recommended treatment plan
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Following pre- and post-treatment advice
Polynucleotides are designed to support skin regeneration and improve skin quality, but exact results cannot be guaranteed. Every treatment is personalised to your skin and concerns, and your clinician will discuss realistic expectations, treatment options and suitability during your consultation so you can make an informed decision.
By proceeding with treatment, you acknowledge that individual responses and outcomes may differ. Our priority is your safety, satisfaction, and achieving natural, harmonious results.


